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关于偏远地区论文范文写作 偏远地区自身免疫性肝病53例临床特点与就诊情况分析相关论文写作资料

主题:偏远地区论文写作 时间:2024-04-21

偏远地区自身免疫性肝病53例临床特点与就诊情况分析,本论文为免费优秀的关于偏远地区论文范文资料,可用于相关论文写作参考。

偏远地区论文参考文献:

偏远地区论文参考文献 临床医学工程杂志中华实用儿科临床杂志临床外科杂志临床和实验医学杂志

DOI:10.16662/j.cnki.1674-0742.2017.07.029

[摘 要] 目的 總结偏远地区自身免疫性肝病的临床特点及就诊情况,达到早诊断、早治疗的目的.方法 回顾性分析曲靖市第二人民医院2013年11月—2016年10月住院的53例自身免疫性肝病的一般情况、临床特点、血清生化学、自身抗体、病理学、影像学及就诊情况.结果 患者平均发病年龄为(56.96±15.6)岁,男:女为1:5.6.AILD临床症状不典型,ALT、AST、ALP、GGT比较差异有统计学意义(P﹤0.05),AIH以ALT、AST升高为主,PBC以ALP、GGT升高为主,AMA、AMA-M2为PBC特异性抗体,AMA阳性率为93.33%,AMA-M2阳性率为90.00%.ANA无特异性,确诊AIH需肝脏病理学.偏远地区因经济文化落后、医务人员对AILD的认识不到位,导致早期诊断率低,发病6个月内确诊率达33.96%(18/53). 结论 偏远地区AILD以围绝经期女性多见,早期症状不典型,生化、免疫学、自身抗体、肝脏穿刺病理学等检查对诊断与鉴别诊断具有重要意义,早期诊断率低.

[关键词] 自身免疫性肝病;临床特点;就诊情况;偏远地区

[中图分类号] R575 [文献标识码] A [文章编号] 1674-0742(2017)03(a)-0029-04

Analysis of Clinical Features and Visit of 53 Cases with Autoimmune Liver Disease in Remote Area

TAI Jing-ping, HUANG Rui-jin, ZHANG Wen-juan

Digestive System Department, Qujing Second People’s Hospital, Qujing, Yunnan Province, 655000 China

[Abstract] Objective To summarize the clinical features and diagnosis situation of 53 cases with autoimmune liver disease in remote area for early diagnosis and treatment. Methods The general conditions, clinical features, serum biochemistry, autoantibody, pathobiology, imaging and diagnosis of 53 cases of inpatients with autoimmune liver disease in our hospital from November 2013 to October 2016 were retrospectively analyzed. Results The erage onset age of children was (56.96±15.6)years old, the ratio of male and female was 1:5.6, the clinical symptoms of AILD was atypical, and the differences in the ALT,AST,ALP,GGT had statistical significance by comparison(P<0.05), and AIH took the increase of ALT and AST as main, PBC took the increase of ALP and GGT as main, and AMA and AMA-M2 were the specific antibodies of PBC, and the positive rate of AMA and AMA-M2 was respectively 93.33% and 90.00%, and ANA had no specificity, and the confirmation of AIH needed the liver pathology, the medical staff’s awareness of AILD was not in place due to the backwards economy and culture, leading to the low early diagnosis rate, and the confirmation rate within 6 months after attack reached 33.96%(18/53). Conclusion AILD is often seen in females during the peri-menopausal period in remote area, and the early symptom is atypical, and the examination of biochemistry, immunology, autoantibodies and liver biopsy pathology is of important significance to the diagnosis and differential diagnosis and the early diagnosis rate is low.

[Key words] Autoimmune liver disease; Clinical feature; Visit; Remote area

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